Program draw peptides

Making the program available to as many users as possible is important to the authors. Installation of PepDraw is as simple as downloading a compressed file and extracting the content, which can be handled by either Windows or Macintosh operating systems. PepDraw can be downloaded from the website for the lab of William Wimley, associate professor of biochemistry. A user must have Java installed on a computer in order for PepDraw to work.

White, W. Wimley, Hydrophobic interactions of peptides with membrane interfaces, Biochimica et biophysica acta Information for Search Tulane. Search form Search. Tulane Home Tulane Home Home. PepDraw Help. PepDraw Web The latest and greatest version of pepdraw is now on the web.

A number of a block where a backbone of a branched or a branch-cyclic peptide is connected to a branch. Names of building blocks forming a backbone of a peptide.

The number of fields is updated when the value of "Number of Blocks at Backbone" is changed. One name of a building block per field must be entered. Summary: I describe a simple standalone program that assists in the preparation of peptide digestion maps. These are useful for comparative studies and for locating peptides within a primary sequence. The program creates an output file as scalable vector graphics that can then be viewed in a web browser or imported into a graphics-editing program.

Availability: The program, as a standalone executable, is available upon request from the author. Contact: r. Although the majority of proteomics applications are driven by the need for global comparisons of protein expression, there are other more specific applications where attention can be focused on a limited number of proteins.

For example, peptide mass fingerprinting can be used to screen for and identify protein polymorphisms provided that there is adequate coverage of the protein sequence by the proteolytic fragments.

The absence of N-terminal or C-terminal fragments can be used to define the approximate sites of proteolysis of a protein fragment. In such studies, it is sometimes necessary to conduct a detailed analysis of a protein and its fragments. Whilst this can be done by comparison of theoretical and observed peptide fragment masses, this can be tedious and error prone.

There is scope for simple visualization tools that can aid interpretation and comparison of proteolytic maps. To meet this need, I have written a simple program that is capable of generating peptide maps from protein sequences Fig. To my knowledge, no such tool exists. This environment is very similar to that provided by a number of other some defunct tools, including Hypercard see, for example, Beynon, , Supercard and Metacard, and is a powerful and rapid application development and prototyping tool.

It provides a comprehensive user interface editor that makes laying out the overall programme window s a trivial task. Objects, such as pulldown menus, dialogue boxes, text fields and graphics are simple to create. Interaction with each object for example, a menu, button or a text field is then mediated through event handlers, defined as scripts associated with that object. The scripting language of Revolution, Transcript, is extremely simple to write and to read, but is sufficiently complex to allow, for example, direct POST operations to a website, use of regular expressions and use of functions and user-defined event handlers.

Transcript code is easy to understand and almost reads like pseudocode.